The increasing number of chemicals entering the market and environment each day requires new and more efficient scientific approaches for assessing and managing chemical risks. SUSPECt tackles this challenge by integrating state-of-the-art scientific knowledge on emission estimation, fate modelling, and effect assessment of chemicals for which limited data are available into a set of decision support tools for contaminants of emerging concern (CEC). Water managers and other parties can use these tools to quantify the human and ecological risks of the current situation and of different future scenarios, e.g. after the introduction of product alternatives, emission reduction measures or enhanced water treatment facilities. SUSPECt will demonstrate in a set of three case studies, i.e. an urban, rural and integrative regional case study, that these tools can be used to stimulate stakeholder involvement, identify costeffective measures, and analyse future scenarios.